What Are the Symptoms of Low Vitamin D?

Symptoms of a vitamin D deficiency include bone problems, muscle aches or cramps, muscle spasms, muscle weakness, fatigue, cognitive impairment (in older adults), severe asthma in children, and cancer.
Symptoms of a vitamin D deficiency include bone problems, muscle aches or cramps, muscle spasms, muscle weakness, fatigue, cognitive impairment (in older adults), severe asthma in children, and cancer.

Vitamin D is a fat-soluble vitamin produced in the skin when it is exposed to sunlight. Vitamin D is also naturally occurring in certain foods such as fatty fish, cod liver oil, and eggs. 

Vitamin D helps the body absorb dietary calcium and phosphorus from the intestines and suppresses the release of parathyroid hormone, a hormone that causes bone resorption. This helps keep bones healthy. Vitamin D is also believed to improve muscle and immune function. 

Vitamin D deficiency is another term for low levels of vitamin D. 

Symptoms of low vitamin D include:

  • Bone problems
    • Pain due to softening of bones (osteomalacia)
    • Fractures
    • Bone deformities such as rickets in children
    • Abnormal bone growth in children aged 1 to 4 years, causing scoliosis, bowlegs, or knock-knees
  • Muscle aches or cramps
  • Muscle spasms
  • Muscle weakness 
  • Fatigue
  • Cognitive impairment in older adults
  • Severe asthma in children
  • Cancer

What Causes Low Vitamin D?

Low vitamin D may be caused by:

  • Low levels of vitamin D in the diet along with inadequate sun exposure
    • Human breast milk contains low levels of vitamin D, and most infant formulas contain inadequate levels of vitamin D
    • Older adults may not consume enough vitamin D-rich foods, and when they do, absorption may be limited
  • Certain conditions that result in an inability to absorb vitamin D from the intestines
    • Crohn's disease
    • Celiac disease
    • Cystic fibrosis
    • Surgery that removes or bypasses portions of the stomach or intestines such as gastric bypass
  • An inability to process vitamin D due to kidney or liver disease
  • Certain medications
  • Other factors
    • Not going outside often, such as those who are ill or housebound
    • Living in institutions such as nursing homes
    • Wearing clothes that cover most of the skin when outdoors
    • Having dark skin, because people with dark skin may not produce sufficient vitamin D from sunlight
    • Obesity

How Is Low Vitamin D Diagnosed?

  • Low levels of vitamin D are diagnosed with a blood test called 25-hydroxyvitamin D or 25(OH)D (OH = hydroxy, D = vitamin D). 
  • X-rays to check the bones may also be indicated. 

What Is the Treatment for Low Vitamin D?

Treatment for low vitamin D includes:

  • Vitamin D supplements
    • Cholecalciferol (vitamin D3) - vitamin D3 is usually recommended because it is the naturally occurring form of the vitamin and it may raise vitamin D levels more effectively
    • Ergocalciferol (vitamin D2) 
    • The recommended dose of vitamin D depends upon the nature and severity of the vitamin D deficiency
  • Additional supplements
    • Calcium 
      • 1000 mg of calcium per day for premenopausal women and men 
      • 1200 mg per day for postmenopausal women

Foods that are good sources of vitamin D include:

  • Oily fish
    • Trout
    • Salmon
    • Sardines
    • Herring
    • Mackerel
    • Tuna
  • Meat and poultry
    • Red meat
    • Beef liver
    • Chicken breast
    • Ground beef
  • Vegetables
    • Mushrooms – white and portabella
  • Dairy products
    • Milk, vitamin D fortified
    • Cheddar cheese
  • Other
    • Cod liver oil
    • Plant-based milks (e.g., soy, almond, oat), vitamin D fortified
    • Egg yolks
    • Ready-to-eat cereals, vitamin D fortified

Exposure to sunlight is a source for vitamin D but too much sun exposure can cause sunburns, premature skin aging, eye damage, heat exhaustion or heat stroke, or skin cancer. Exposure to the sun is not recommended as a source of vitamin D for infants and children because of the potential risks of skin cancer. Talk to your doctor about how much sun exposure you need and how to get sun exposure safely.

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References
https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/

https://www.uptodate.com/contents/vitamin-d-deficiency-beyond-the-basics?search=vitamin%20d%20deficiency&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2

https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-d/

https://www.merckmanuals.com/home/disorders-of-nutrition/vitamins/vitamin-d-deficiency