Chlorpheniramine maleate (brand name Chlor-Trimeton) is an antihistamine used to treat sneezing, watery eyes, runny nose, and itching of the eyes, nose, or throat caused by allergies or the common cold.
- Chlorpheniramine maleate is also used off-label (use not approved by the Food and Drug to treat motion sickness in adults.
- Chlorpheniramine maleate is available over-the-counter (OTC) and as a generic.
What Are Side Effects of Chlorpheniramine Maleate?
Common side effects of chlorpheniramine maleate include:
- Drowsiness
- Mild dizziness
- Fatigue
- Blurred vision
- Dry mouth
- Sore throat
- Nausea
- Stomach pain
- Constipation
- Headache
- Nervousness
- Diarrhea
- Increased appetite
- Urinary retention
- Increased urination
- Joint pain
- Weakness
- Double vision
- Problems with memory or concentration
- Weight gain
- Restlessness or excitability (especially in children)
What Is the Dosing for Chlorpheniramine Maleate?
- The dose for chlorpheniramine maleate for adults and children 12 years of age and older is one tablet every 4 to 6 hours, not to exceed 6 tablets in 24 hours or as directed by a physician.
- The dose for chlorpheniramine maleate for children 6 through 11 years is half the adult dose every 4 to 6 hours, not to exceed 3 whole tablets in 24 hours.
- Consult a doctor for children under 6 years.
What Are Drug Interactions of Chlorpheniramine Maleate?
Chlorpheniramine maleate may interact with other drugs, such as:
- Antidepressants
- Aspirin or salicylates
- Atropine
- Belladonna
- Benztropine
- Bladder or urinary medications
- Bronchodilators
- Dimenhydrinate
- Diuretics (water pills)
- Glycopyrrolate
- Irritable bowel medications
- Mepenzolate
- Methscopolamine
- Monoamine oxidase inhibitors (MAOIs)
- Scopolamine
Tell your doctor of all drugs you are taking.
Can Chlorpheniramine Maleate Be Used During Pregnancy or While Breastfeeding?
Tell your doctor if you are pregnant or plan to become pregnant while taking chlorpheniramine maleate. Chlorpheniramine maleate is not expected to harm a fetus.
Chlorpheniramine maleate passes into breast milk and may harm a nursing infant. Consult your doctor before breastfeeding.
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Reviewed on 8/3/2022
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REFERENCES:
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Image source: iStock Images
https://www.uptodate.com/contents/chlorpheniramine-drug-information?search=Chlorpheniramine%20Maleate%20&source=search_result&selectedTitle=1~141&usage_type=default&display_rank=1#F149968